知识与财富的链接
目的 优选肝脂消胶囊的乙醇提取工艺. 方法 以肝脂消胶囊中虎杖和大黄中的总蒽醌含量作为考察指标,采用L9（34）正交实验进行筛选,考察乙醇浓度、乙醇用量、提取时间、提取次数等因素以确定最佳的提取工艺. 结果 提取次数和乙醇浓度对提取效果影响有显著意义,最佳工艺为70%乙醇,7倍量溶剂,每次提取2 h,提取3次. 结论 该实验所优选的提取工艺稳定、可靠,可用于实际生产制备.
Objective To optimize the alcoholic extraction technique of ganzhixiao capsule. Methods The total contents of anthraquinone from ganzhixiao capsules were regarded as the indicator,and L9(34) orthogonal study was applied to observe the concentration and amount of alcohol,extracting time and times of extraction in order to determine the best extracting technique. Results The times of extraction and the concentration of alcohol were the most significant factors,and the optimal extraction process required 70% alcohol,7 times amount of solvent,3 times extraction,2 h for each. Conclusion The results show that the extraction technique was stable,reliable and eligible for manufacturing instruments.
